Trulieve Orlando

4600 E Colonial Dr, Orlando, FL 32803 — Orlando Cannabis Dispensary

Medical Only (FL MMTC Patient Card Required) ★★★★☆ 4.7/5 Open Today
Address4600 E Colonial Dr, Orlando, FL 32803
HoursDaily: 9am-9pm
Legal StatusMedical Cannabis - Florida (MMTC Patient Card Required)

About Trulieve Orlando

Trulieve is Florida's largest Medical Marijuana Treatment Center (MMTC) by outlet count, operating dozens of dispensaries statewide. The Orlando East Colonial Drive location is among the company's busiest, serving the Orange County medical patient base with a full range of cannabis products available only to registered Florida medical marijuana patients.

Florida's medical cannabis program requires patients to obtain a physician certification and register with the Florida Department of Health to receive a Medical Marijuana Use Registry ID card. Qualifying conditions include cancer, epilepsy, glaucoma, PTSD, ALS, Crohn's disease, Parkinson's disease, MS and other debilitating conditions as determined by a licensed physician. Trulieve stocks flower, tinctures, capsules, vapes, concentrates and topicals.

The East Colonial location features a modern retail environment with efficient service and digital ordering integration. The TruRewards loyalty program offers points on every purchase. New patient onboarding sessions are available to help first-time cardholders navigate the dispensary and understand their options.

Popular Strains at This Dispensary

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Reviewed by Marcus Webb, Cannabis Industry Researcher. Last updated: 2025.

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