Greenleaf Apothecaries Ann Arbor

615 S Main St, Ann Arbor — Medical and Recreational Cannabis - Michigan

Medical and Recreational Cannabis - Michigan ★★★★☆ 4.5/5 Open Today
Address615 S Main St, Ann Arbor 48104
HoursMon–Sat: 9am–9pm • Sun: 10am–8pm
Legal StatusMedical and Recreational Cannabis - Michigan

About Greenleaf Apothecaries Ann Arbor

Greenleaf Apothecaries takes a wellness-first approach to cannabis retail, with an interior that draws inspiration from traditional herbal apothecaries. The Ann Arbor location on South Main serves the downtown core and is particularly popular with medical patients seeking tinctures, topicals and CBD-rich products. Staff training emphasizes interaction with the endocannabinoid system and non-intoxicating therapeutic options.

Beyond medical products, Greenleaf stocks a full recreational menu including flower, prerolls, vape cartridges and edibles. The selection of topicals including balms, patches and lotions is among the most extensive in Washtenaw County, catering to customers seeking localized relief without systemic effects. A pharmacist-trained consultant is on staff on weekdays.

South Main Street is walkable from the downtown Ann Arbor core and accessible by foot from the Blake Transit Center. The store accepts both cash and debit. Parking is available in the adjacent municipal structure. Discounts apply for veterans, seniors, low-income patients and those enrolled in Michigan Cannabis Social Equity programs.

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Reviewed by Marcus Webb, Cannabis Industry Researcher. Last updated: 2025.

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